Composition: - Each 1 gm contains Oxytetracycline hydrochloride       757 mg Equi. To oxytetracycline base         700 mg Properties :

Oxytetracycline is a broad-spectrum antibiotic. It is mainly active against Gram-positive and Gram negative bacteria, aerobic and anaerobic, mycoplasma, Chlamydia and Rickettsiae It acts by reversibly to the ribosomal subunit 30S receptors to a blockage of the union between aminoacyl-tRNA to the site corresponding to the mRNA-ribosome complex messenger. Then inhibition of the protein synthesis and inhibits bacterial growth. Indications: Chicktetra is used for the treatment of: Broiler chickens: *Arthritis caused by Staphylococcus aureus. *Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum. *Infectious enteritis caused by E. coli. *Fowl cholera caused by Pasteurella multocida. *Fowl coryza caused by Haemophilus paragallinarum. *Gangrenous dermatitis caused by Clostridium spp. *Typhoid & paratyphoid caused by Salmonella  spp. Pre – ruminating calves: *Bovine pneumonia caused by Mycoplasma bovis , Pasteurella haemolytica , P. multocida & Haemophilus somnus. *Scours , neonatal diarrhea  caused by E. coli & Salmonella  spp. Target Species Broiler Chickens ,pre-ruminating calves Dosage and administration:

  by addition to drinking water From active ingredient  : Broiler chickens: 20mg of oxytetracycline /kg body weight 3-5 days Pre – ruminating calves: 10-30 mg / kg bodyweight 1-2 times daily From whole product Broiler chickens: 0.5 gm of product / liter of drinking water 3-5 days Pre – ruminating calves: 2.5gm7.5gm  of product /100 kg body weight 1-2 times daily Warning and precautions : Should be dissolved in water, before use. Prolonged or repeated use should be avoided Do not use in laying birds producing eggs intended for human consumption Contra indications hypersensitivity to oxytetracycline or any other substance from tetracyclines group. Side effects:  gastro-intestinal disorder and less frequently, allergic and photosensitivity reactions. Interaction with other drugs: should not be administered with antacids, gels containing aluminium, preparations containing vitamins or minerals as insoluble complexes will be formed, which decreases the absorption of the antibiotic. Withdrawal period Meat and offal:7 days Eggs: do not use in laying birds producing eggs intended for human consumption Storage: Keep on cool &dry place not exceeding 30° C. Keep out of reach of children. Manufactured by Eva pharm distribution by "Aleffat trading "

Composition : Each 1 gm contains: - Doxycycline (as hyclate) 400 mg + Bromhexine (as hydrochloride) 40 mg Properties : Doxycycline: has broad spectrum activity inhibiting both aerobic and anaerobic gram-posi�tive and gram-negative bacteria, mycoplasmas, chlamydiae, rickettsias and some protozoa. Bromhexine is a mucoregulator. By activating the secretion of the seromucous glands, It breaks down the network of acid glycoprotein fibres found in mucoid sputum, which are mainly responsible for the characteristic viscosity. Mechanism of Action: Doxycycline inhibits bacterial protein synthesis. Doxycycline binds to the 30S ribosomal subunit, which prevents the tRNA from binding to the ribosome. This prevents the mRNA from being translated into protein, which is essential for bacterial growth and reproduction. Bromhexine acts by inhibiting neuraminidase, stabilizing lysosomes, increasing ciliary activity, hydrating mucus, and exhibiting anti-inflammatory effects. Strength points of Hexacycline: Hexacycline Synergistic effect: Doxycycline is a broad-spectrum antibiotic that is effective against a wide range of bacteria, including Mycoplasma gallisepticum, which is a common cause of respiratory infections in poultry. Bromhexine is an expectorant that helps to loosen mucus and clear congestion. When used together, doxycycline and bromhexine can be more effective than either drug alone in treating respiratory infections. Hexacycline Improved absorption: Bromhexine can help to improve the absorption of doxy�cycline, which means that it is effective in the lower doses. Hexacycline is effective against a wide range of Gram-positive and Gram-negative bacteria, making it a versatile antibiotic for poultry. Hexacycline has a long half-life, meaning it remains in the body for an extended period, providing prolonged protection against bacterial infections. Hexacycline Reduced Respiratory Distress: By assisting in clearing mucus and improving airway function, bromhexine may contribute to reducing respiratory distress in affected poultry Dose of whole product: Broilers chickens: 0.5 gm of the product / 1 liter drinking water Produced by EVA PHARMA distributor by Aleffat trading